Hi, I’m Arun and I develop novel neurotechnologies to interface with the brain.

Current Research

Explore my ongoing projects in neural engineering and neurotechnology development.

A high-performance neuroimaging platform for ultra-large field of view cortex-wide calcium imaging in minimally restrained mammals.

A tracking robot system for high-throughput behavior recordings in freely moving mammals

Role: Co-author

We're innovating a novel method for capturing fast voltage signals (> 200Hz) in cortical neuronal populations of freely behaving mice. Our methodology aims to achieve high throughput illumination, high speed, sensing, and downstream hardware for data interfacing with miniature devices that would allow high bandwidth data transmission without hindering the free behavior of animals.

3D printed flexible electrocorticography (ECoG) arrays for simultaneous imaging and electrophysiology in behaving mammals

Role: Lead Author

I've developed a novel optical design framework using miniature optical components and high-sensitivity back-illuminated CMOS sensors that enable the capture of individual calcium transients in thousands of cells spanning 48 mm square region of the dorsal cortical surface. I have also devised a mechanical assemblage that offsets the weight of this high-performance imaging system, allowing the animals to explore 2D spatial environments while tethered to the neuroimaging platform

Role: Co-author

We are currently developing graphene 3D printed flexible, transparent and high-density ECoG arrays. This will give us the capability to record bilateral cortical neural activity using upto 64 electrode channels. Moreover, we could combine these recordings with mesoscale calcium imaging to study cortex-wide neurodynamics. The electrode arrays can give us the temporal resolution needed to detect spiking activity and the imaging data can give us the desired spatial resolution.

High-speed simultaneous voltage imaging of multiple cell types in the dorsal cortex of freely behaving mammals

Role: Lead Author

This project entails the development of low-latency actuated gantry system with end effector modified to carry upto 1.5 kilograms of neuroimaging payload. This will allow us to extend the capability of gantry-supported behavior assays.